The treatment of complicated and severe malaria

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The treatment of complicated and severe malaria.

All cases of falciparum malaria are potentially severe and life threatening, especially when managed inappropriately. A major reason for progression from mild through complicated to severe disease is missed or delayed diagnosis. Once diagnosed, the priority for treatment of complicated and severe disease is the parenteral administration of adequate, safe doses of an appropriate antimalarial, in...

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Prognostic factors in severe and complicated malaria.

Background: The spectrum of clinical picture of malaria ranges from the most benign febrile illness, which is completely curable with a simple course of chloroquine tablets to the most serious and life-threatening illness, even with very drastic therapeutic measures. That is the reason that has led to the studies from different parts the world to find out the clinical and laboratory parameters ...

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Artesunate: The Best Drug in the Treatment of Severe and Complicated Malaria

This review summarizes progress in treating severe and complicated malaria, which are global problems, claiming at least one million lives annually, and have been accompanied by advances in our understanding of the pathogenesis of severe malaria complications. New drugs such as intravenous artesunate (AS) and intramuscular artemether (AM) are improving outcomes and decreasing malaria deaths. Tr...

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Severe Malaria and Artesunate Treatment, Norway

To the Editor: Approximately 8,000 cases of imported falciparum malaria are reported in Europe each year (1). In a study from Belgium of 1,743 persons with fever acquired in the Tropics, only falciparum malaria resulted in deaths (2). Until recently, the standard treatment of severe malaria was intravenous quinine (3). Frequent adverse effects, however, and reports of limited clinical effi cacy...

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ژورنال

عنوان ژورنال: British Medical Bulletin

سال: 2005

ISSN: 1471-8391,0007-1420

DOI: 10.1093/bmb/ldh059